Resiniferatoxin (57444-62-9) Score: #1264 in Neuroscience, #5426 in Biology, #7271 in Chemistry "What do you need help with?" The Adooq dilution calculator is based on the following equation: Concentration(start) x Volume(start) = Concentration(final) x Volume(final), This equation is commonly abbreviated as: C1V1 = C2V2. Resiniferatoxin (CAS NO.57444-62-9) is white to off-white solid. Registered codes will be associated with your order and points will be awarded ($1 = 1 point). Resiniferatoxin is a potent and selective agonist of the TRPV1 (Vanilloid/Capsaicin receptor) channel. The Resiniferatoxin is a chemical compound that is gained by resin spurge. Compare Products: Select up to 4 products. Total Synthesis of Resiniferatoxin Enabled by Radical-Mediated Three-Component Coupling and 7-endo Cyclization. Regulation. Journal of the American Chemical Society 2017 , 139 (45) , 16420-16429. Free shipping on inhibitor and protein orders over $500. It is an agonist of the transient receptor potential cation channel subfamily V member 1 (TrpV1). Contact No. Outcome Measures. sale Price: $24.95 ( You save $14.05 ) HotSauce . These canals take too much calcium into the cell, poisoning the cell and killing it. Item Code: HSC-16-Million-Crystals2.0. Keywords:buy Resiniferatoxin | Resiniferatoxin Supplier | purchase | cost | manufacturer | order | distributor | buy 57444-62-9| 57444-62-9 Supplier | purchase 57444-62-9 | 57444-62-9 cost | 57444-62-9 manufacturer | order 57444-62-9 | 57444-62-9 distributor, Check our recent promotion and sale events, AdScreen™ MAPK Inhibitor Compound Library, AdScreen™ PI3K/Akt/mTOR Inhibitor Compound Library, Publications Citing Use of Adooq Resiniferatoxin, CC1CC2(C3C4C1(C5C=C(C(=O)C5(CC(=C4)COC(=O)CC6=CC(=C(C=C6)O)OC)O)C)OC(O3)(O2)CC7=CC=CC=C7)C(=C)C, Thieu X. Phan, .et al. What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution? Orders valued at $1000, will receive 400 points. We don't know when or if this item will be back in stock. Health Effects: Resiniferatoxin is a neurotoxin that targets afferent sensory neurons involved in nociception. For Research Use Only RTX Store at -20C Chemical appearance: Solid Purity: >99% Specifications for this item. This fits your . Site Use Terms
THE HOT ONES; HOTTEST DAILY DEALS! USA; Globally; Search term: "resiniferatoxin" Compare Products: Select up to 4 products. Home. Get Get resources and offers direct to your inbox. 1 Application of sub-nanomolar concentrations of Resiniferatoxin irreversibly induces a sustained slow current and depolarization in DRG neurons. ZTlido ® was approved by the FDA on February 28, 2018. Resiniferatoxin binds to a protein called VR1, which is a channel on the surface of certain types of pain-sensing nerve cells. Questions? Objectives To evaluate the efficacy of resiniferatoxin in the treatment of patients with lifelong premature ejaculation. Not for human use. For the treatment, the glans were respectively soaked in 30 mL of resiniferatoxin with a concentration of 100 nmol/L or 10% alcohol solution for 30 min before sexual intercourse. It is up to one thousand times stronger than pure capsaicin. *The above data is based on the productmolecular weight 628.7. Currently unavailable. Capsazepine (1 µM) blocks capsaicin (60 nM) stimulated firing of C-fibers. Brand Name: INDOFINE Chemical Company Grade Rating: Research … The abbreviation of resiniferatoxin is RTX that is extremely popular for carrying massive Scoville Heat Units which are generally used to cure some severe, lasting and critical pains in the human body. Make sure this fits by entering your model number. J.Pharmacol.Exp.Ther., 1990;255:923 Cellular mechanism of action of resiniferatoxin: a potent sensory neuron excitotoxin. The Pain Life Science Poster is part of the range of life science posters produced by Tocris and authored by leading experts in the field. Resiniferatoxin is a natural analog of capsaicin isolated from some plants of the genus Euphorbia, including E. resinifera. The Adooq dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Please post your buying leads,so that our qualified suppliers will soon contact you! Resiniferatoxin Chemical Structure CAS NO. Available for Sale. TRPV1 expressed throughout the arterial circulation regulates vasoconstriction, bioRxiv, 2020, February 04, Enter 10 into the Concentration (start) box and select the correct unit (millimolar), Enter 50 into the Concentration (final) box and select the correct unit (micromolar), Enter 20 into the Volume (final) box and select the correct unit (milliliter), The answer of 100 microliter (0.1 ml) appears in the Volume (start) box, mass of a compound required to prepare a solution of known volume and concentration, volume of solution required to dissolve a compound of known mass to a desired concentration, concentration of a solution resulting from a known mass of compound in a specific volume, Enter 197.13 into the Molecular Weight (MW) box, Enter 10 into the Concentration box and select the correct unit (millimolar), Enter 10 into the Volume box and select the correct unit (milliliter), The answer of 19.713 mg appears in the Mass box. We had an intriguing conversation regarding resiniferatoxin, pure capsaicin, and chili peppers. Sigma-Aldrich Products are sold exclusively through Sigma-Aldrich, Inc.